Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.69 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.69 |
| ▸ | MMP2 | P08253 | 2/20 | 0.69 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.69 |
| ▸ | RAD52 | P43351 | 1/20 | 0.63 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040639 | 1.00 | PSMD14 (0.69) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL2912562 | 0.98 | PSMD14 (0.72) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL11227182 | 0.98 | PSMD14 (0.72) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL11215399 | 0.98 | PSMD14 (0.72) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL11875761 | 0.98 | PSMD14 (0.72) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL11595988 | 0.90 | PLA2G1B (0.74) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL11527519 | 0.90 | PLA2G1B (0.74) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL11596806 | 0.90 | PLA2G1B (0.74) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL27937629 | 0.90 | PLA2G1B (0.74) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL28668483 | 0.90 | PLA2G1B (0.74) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240052276-A9 | FLEXIBLE, POROUS, DISSOLVABLE SOLID SHEET ARTICLES CONTAINING CATIONIC SURFACTANT | THE PROCTER AND GAMBLE COMPANY | 2024-02-15 | — | — | US | claimed |
| US-20110281785-A1 | FABRIC ENHANCERS COMPRISING NANO-SIZED LAMELLAR VESICLE | GIZAW YONAS (US) | 2011-11-17 | — | — | US | claimed |
| US-7928055-B2 | Clear and/or translucent fabric enhancers comprising nano-sized particles | THE PROCTER & GAMBLE COMPANY (US) | 2011-04-19 | — | — | US | claimed |
| EP-2049640-A2 | CLEAR AND/OR TRANSLUCENT FABRIC ENHANCERS COMPRISING NANO-SIZED PARTICLES | The Procter and Gamble Company (US) | 2009-04-22 | — | — | EP | claimed |
| EP-2049639-A1 | FABRIC ENHANCERS COMPRISING NANO-SIZED LAMELLAR VESICLE | The Procter and Gamble Company (US) | 2009-04-22 | — | — | EP | claimed |
| US-20090042767-A1 | Clear and/or translucent fabric enhancers comprising nano-sized particles | THE PROCTER & GAMBLE COMPANY | 2009-02-12 | — | — | US | claimed |
| US-20090042765-A1 | Fabric enhancers comprising nano-sized lamellar vesicle | PROCTER & GAMBLE COMPANY, THE | 2009-02-12 | — | — | US | claimed |
| US-20080263780-A1 | Fabric enhancing compositions comprising nano-sized particles and anionic detergent carry over tollerance | THE PROCTER & GAMBLE COMPANY | 2008-10-30 | — | — | US | claimed |
| WO-2008021893-A1 | FABRIC ENHANCING COMPOSITIONS COMPRISING NANO-SIZED PARTICLES AND ANIONIC DETERGENT CARRY OVER TOLLERANCE | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-21 | — | — | WO | claimed |
| WO-2008021895-A2 | CLEAR AND/OR TRANSLUCENT FABRIC ENHANCERS COMPRISING NANO-SIZED PARTICLES | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-21 | — | — | WO | claimed |
| WO-2008021892-A1 | FABRIC ENHANCERS COMPRISING NANO-SIZED LAMELLAR VESICLE | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-21 | — | — | WO | claimed |
| EP-4399269-A1 | PHENOLIC COMPOSITIONS FOR MALODOR REDUCTION | Milliken & Company (US) | 2024-07-17 | — | — | EP | disclosed |
| US-12031113-B2 | Composition comprising hueing agent | MILLIKEN & COMPANY (US) | 2024-07-09 | — | — | US | disclosed |
| US-12018232-B2 | Multilayer dissolvable solid article containing solid particles for making the same | THE PROCTER & GAMBLE COMPANY (US) | 2024-06-25 | — | — | US | disclosed |
| US-20240197579-A9 | MULTILAYER DISSOLVABLE SOLID ARTICLE CONTAINING COATING COMPOSITION AND PROCESS FOR MAKING THE SAME | THE PROCTER AND GAMBLE COMPANY | 2024-06-20 | — | — | US | disclosed |
| WO-1998008924-A2 | CONCENTRATED PREMIX WITH REDUCED FLAMMABILITY FOR FORMING FABRIC SOFTENING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| WO-1998003619-A1 | CONCENTRATED FABRIC SOFTENING COMPOSITION AND HIGHLY UNSATURATED FABRIC SOFTENER COMPOUND THEREFOR | THE PROCTER & GAMBLE COMPANY (US) | 1998-01-29 | — | — | WO | disclosed |
| WO-1997034976-A1 | CONCENTRATED, STABLE, PREMIX FOR FORMING FABRIC SOFTENING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-25 | — | — | WO | disclosed |
| WO-1997034975-A1 | CONCENTRATED FABRIC SOFTENING COMPOSITION WITH GOOD FREEZE/THAW RECOVERY AND HIGHLY UNSATURATED FABRIC SOFTENER COMPOUND THEREFOR | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-25 | — | — | WO | disclosed |
| WO-1997003170-A1 | CONCENTRATED, WATER DISPERSIBLE, STABLE, FABRIC SOFTENING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240197579-A9 | MULTILAYER DISSOLVABLE SOLID ARTICLE CONTAINING COATING COMPOSITION AND PROCESS FOR MAKING THE SAME | SEPTIN8, DSTN, SEPTIN2 | PSMD14 463/4885PLA2G1B 2015/4885MMP2 1029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.