Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SOD1 | P00441 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125877 | 0.89 | NPC1 (0.42) | NPC1ALDH1A1TSHRKMT2ARAB9A | |
| SCHEMBL29126006 | 0.81 | TSHR (0.47) | ALDH1A1TSHRKMT2AHSD17B10MMP13 | |
| SCHEMBL29128357 | 0.80 | SOD1 (0.36) | NPC1SOD1PPARDLMNAMAPT | |
| SCHEMBL29125958 | 0.75 | ALDH1A1 (0.38) | NPC1ALDH1A1TSHRKMT2AHSD17B10 | |
| SCHEMBL29125947 | 0.73 | TSHR (0.40) | NPC1ALDH1A1TSHRKMT2AHSD17B10 | |
| SCHEMBL29128540 | 0.73 | NPC1 (0.33) | NPC1ALDH1A1SOD1GAA | |
| SCHEMBL29125813 | 0.71 | TSHR (0.46) | ALDH1A1TSHRKMT2AHSD17B10RAB9A | |
| SCHEMBL29125834 | 0.71 | KMT2A (0.41) | ALDH1A1TSHRKMT2AHSD17B10SOD1 | |
| SCHEMBL29125709 | 0.71 | TSHR (0.36) | NPC1TSHRHSD17B10RAB9AMAPT | |
| SCHEMBL29125955 | 0.69 | LMNA (0.46) | NPC1ALDH1A1TSHRKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |