Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.64 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057736 | 0.90 | ADRA1A (0.56) | HTR2CDRD2DDB1CRBNADRA1A | |
| SCHEMBL1515134 | 0.86 | HTR2C (0.77) | HTR2CDRD2DDB1CRBNADRA1A | |
| SCHEMBL30997824 | 0.86 | HTR2C (0.77) | HTR2CDRD2DDB1CRBNADRA1A | |
| SCHEMBL14613763 | 0.83 | HTR2C (0.64) | HTR2CDRD2DDB1CRBNADRA1A | |
| SCHEMBL23705886 | 0.83 | HTR2C (0.58) | HTR2CDRD2DDB1CRBNADRA1A | |
| Methyl Alcohol SCHEMBL8097139 | 0.82 | HTR2C (0.72) | HTR2CDRD2DDB1CRBNADRA1A | |
| SCHEMBL7844832 | 0.82 | HTR2C (0.72) | HTR2CDRD2DDB1CRBNADRA1A | |
| SCHEMBL1515075 | 0.82 | HTR2C (0.72) | HTR2CDRD2DDB1CRBNADRA1A | |
| SCHEMBL3161832 | 0.82 | PDE4A (0.52) | HTR2CDDB1CRBNPDE4APDE4B | |
| SCHEMBL4359622 | 0.81 | CYP3A4 (0.49) | HTR2CPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250363-B1 | TRIAZINE DERIVATIVES OF PIPERIDINYLAMIDINES | CIBA-GEIGY AG (CH) | 1990-11-28 | — | — | EP | claimed |
| JP-5059165-A | — | — | None | — | — | JP | disclosed |
| CN-113861077-A | Method for preparing p-phenylene diisocyanate by non-phosgene method | 王植源 | 2021-12-31 | — | — | CN | disclosed |
| US-20210393623-A1 | Novel Heterocyclic Derivatives Useful as SHP2 Inhibitors | JACOBIO PHARMACEUTICALS CO LTD (CN) | 2021-12-23 | — | — | US | disclosed |
| CN-111712490-A | Amino-substituted pyridone derivatives, preparation method and medical application thereof | 上海海雁医药科技有限公司 | 2020-09-25 | — | — | CN | disclosed |
| WO-2020063760-A1 | NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2020-04-02 | — | — | WO | disclosed |
| US-9796139-B2 | Three-dimensional shaping composition, method for producing three-dimensionally shaped article, and three-dimensionally shaped article | SEIKO EPSON CORPORATION (JP) | 2017-10-24 | — | — | US | disclosed |
| US-20160108259-A1 | THREE-DIMENSIONAL SHAPING COMPOSITION, METHOD FOR PRODUCING THREE-DIMENSIONALLY SHAPED ARTICLE, AND THREE-DIMENSIONALLY SHAPED ARTICLE | SEIKO EPSON CORPORATION (JP) | 2016-04-21 | — | — | US | disclosed |
| US-8808948-B2 | Dispersion composition, photosensitive resin composition for light-shielding color filter, light-shielding color filter, method of producing the same, and solid-state image sensor having the color filter | FUJIFILM CORPORATION (JP) | 2014-08-19 | — | — | US | disclosed |
| US-8507100-B2 | Primer, conductor foil with resin, laminated sheet and method of manufacturing laminated sheet | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20030229200-A1 | Selective linear peptides with melanocor tin-4 receptor (MC4-R) agonist activity | CHEN LI (US) | 2003-12-11 | — | — | US | disclosed |
| US-6600015-B2 | Treatment or prevention of obesity. | HOFFMANN-LA ROCHE INC. | 2003-07-29 | — | — | US | disclosed |
| EP-1315750-A2 | CYCLIC PEPTIDES HAVING MELANOCORTIN-4 RECEPTOR AGONIST ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-04 | — | — | EP | disclosed |
| EP-1272516-A2 | SELECTIVE LINEAR PEPTIDES WITH MELANOCORTIN-4 RECEPTOR (MC4-R) AGONIST ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2003-01-08 | — | — | EP | disclosed |
| US-20020143141-A1 | Selective cyclic peptides with melanocortin-4 receptor (MC4-R) agonist activity | CHEN LI (US) | 2002-10-03 | — | — | US | disclosed |
| WO-2002018437-A2 | CYCLIC PEPTIDES HAVING MELANOCORTIN-4 RECEPTOR AGONIST ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-07 | — | — | WO | disclosed |
| US-20010056179-A1 | Selective linear peptides with melanocortin-4 receptor (MC4-R) agonist activity | HOFFMANN-LA ROCHE INC. | 2001-12-27 | — | — | US | disclosed |
| WO-2001074844-A2 | SELECTIVE LINEAR PEPTIDES WITH MELANOCORTIN-4 RECEPTOR (MC4-R) AGONIST ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-11 | — | — | WO | disclosed |
| JP-H0559165-A | POLYCARBONATE OF BISHYDROXYCYCLOHEXYLESTER | CHISSO CORP | 1993-03-09 | — | — | JP | disclosed |
| US-3960802-A | Process for the manufacture of a one-component room-temperature vulcanizable silicone composition | GENERAL ELECTRIC COMPANY (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143141-A1 | Selective cyclic peptides with melanocortin-4 receptor (MC4-R) agonist activity | MC4R, MC3R, MC1R | HTR2C 568/4885DRD2 1293/4885DDB1 4647/4885 |
| US-20030229200-A1 | Selective linear peptides with melanocor tin-4 receptor (MC4-R) agonist activity | MC4R, MC1R, MC3R | HTR2C 247/4885DRD2 850/4885DDB1 4290/4885 |
| US-20210393623-A1 | Novel Heterocyclic Derivatives Useful as SHP2 Inhibitors | PTPN1, PTPN5, PTPN2 | HTR2C 3677/4885DRD2 4863/4885DDB1 1845/4885 |
| US-20010056179-A1 | Selective linear peptides with melanocortin-4 receptor (MC4-R) agonist activity | MC4R, MC3R, MC1R | HTR2C 239/4885DRD2 1017/4885DDB1 4390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.