SCHEMBL2912804

SCHEMBL2912804

O=[PH](OCC(O)CO)OCC(O)CO

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.40
ALDH1A1 P00352 1/20 0.40
USP2 O75604 1/20 0.34
KDM4E B2RXH2 2/20 0.34
DUSP3 P51452 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
THRB P10828 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
CYP1A2 P05177 2/20 0.31
AGTR1 P30556 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28564071 0.86 LMNA (0.35) LMNAALDH1A1USP2KDM4EDUSP3
SCHEMBL27886174 0.83 ALDH1A1 (0.31) LMNAALDH1A1
SCHEMBL2912805 0.82
SCHEMBL15887085 0.82
SCHEMBL28229216 0.81 SMN1; SMN2 (0.50) LMNAUSP2SMN1; SMN2
SCHEMBL15887074 0.81 USP2 (0.33) USP2SMN1; SMN2
SCHEMBL159440 0.81 SMN1; SMN2 (0.50) LMNAUSP2SMN1; SMN2
SCHEMBL14047309 0.81 USP2 (0.33) USP2SMN1; SMN2
SCHEMBL26661989 0.81 SMN1; SMN2 (0.50) LMNAUSP2SMN1; SMN2
SCHEMBL27832027 0.80 LMNA (0.36) LMNAALDH1A1USP2KDM4EDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106456545-A Immunogenic liposomal formulation 葛兰素史密丝克莱恩生物有限公司 2017-02-22 CN claimed
WO-2016014539-A1 PHOSPHONIC ACID COMPOUNDS AND SCREENING METHOD THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2016-01-28 WO claimed
CN-105209041-A Novel respiratory control modulating compounds and methods of use thereof GALLEON PHARMACEUTICALS INC 2015-12-30 CN claimed
US-20250325569-A1 COMPOSITIONS AND METHODS OF MAKING AND USE THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2025-10-23 US disclosed
CN-118852530-A Phosphoglyceride-based polymer and preparation method and application thereof 湖北工程学院 2024-10-29 CN disclosed
WO-2023200968-A1 COMPOSITIONS AND METHODS OF MAKING AND USE THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2023-10-19 WO disclosed
CN-110746518-A Preparation method of high-purity ganoderma lucidum polysaccharide 西藏天虹科技股份有限责任公司 2020-02-04 CN disclosed
CN-110452262-A The synthetic method of platelet activating factor (PAF) analog AMTECH BIOENGINEERING LTD INC 2019-11-15 CN disclosed
CN-104367997-B Adjunvant composition comprising nonionic isotonic agent 葛兰素史密丝克莱恩生物有限公司 2019-01-22 CN disclosed
CN-108602866-A Expression and folding in CD-RAP preparation process is improved by using CD-RAP precursor proteins 生命制药有限责任公司 2018-09-28 CN disclosed
CN-107735383-A Cement tile adhesive composition containing cross-linked cellulose ether for mortars with enhanced gel strength 陶氏环球技术有限责任公司 2018-02-23 CN disclosed
CN-1151777-C Preparation for transport of active substance across barriers �����ɷ� 2004-06-02 CN disclosed
CN-1283107-A Methods of developing, testing and using complexes of macromolecules and complex aggregates for improved payload and controllable dissociation/association rates IDED INNOVATIVE DERMALE APPLIK (DE) 2001-02-07 CN disclosed
CN-1234736-A Preparation for transport of active substance across barriers IDEA INNOVAT DERMALE APPL GMBH (DE) 1999-11-10 CN disclosed
US-5130308-A Indole derivatives as anticarcinogenic agents ASTA PHARMA (DE) 1992-07-14 US disclosed
US-4992553-A Treatment of hormone dependent tumors ASTA PHARMA AKTIENGESELLSCHAFT (DE) 1991-02-12 US disclosed
US-4847297-A AIDS TREATMENT DEGUSSA AKTIENGESELLSCHAFT (DE) 1989-07-11 US disclosed
US-4730068-A SPECIAL EFFECT ON BREAST CANCER ASTA-WERKE AKTIENGESELLSCHAFT (DE) 1988-03-08 US disclosed
US-4704464-A CHELATE COMPOUNDS ASTA-WERKE AKTIENGESELLSCHAFT CHEMISCHE FABRIK (DE) 1987-11-03 US disclosed
US-4598091-A (1,2-diphenyl)-ethylenediamine)-platinum (II) complex compounds DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325569-A1 COMPOSITIONS AND METHODS OF MAKING AND USE THEREOF PGLS, PLA2G2C, PPA1 LMNA 3836/4885ALDH1A1 1878/4885USP2 3814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.