Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128413 | 0.87 | HTT (0.41) | HTTTDP1NPSR1LMNAALDH1A1 | |
| SCHEMBL29128195 | 0.85 | MAPT (0.32) | NPSR1KDM4EMAPK1MAPT | |
| SCHEMBL29128415 | 0.82 | MAPT (0.37) | HTTTDP1NPSR1LMNAALDH1A1 | |
| SCHEMBL29128412 | 0.81 | ALDH1A1 (0.32) | ALDH1A1KDM4EGAA | |
| SCHEMBL29128302 | 0.81 | APP (0.35) | HTTTDP1LMNAALDH1A1MEN1 | |
| SCHEMBL29128368 | 0.79 | ALDH1A1 (0.49) | HTTTDP1LMNAALDH1A1KDM4E | |
| SCHEMBL29128376 | 0.79 | KMT2A (0.31) | HTTLMNAALDH1A1KMT2A | |
| SCHEMBL29128211 | 0.78 | — | — | |
| SCHEMBL29128402 | 0.78 | RAB9A (0.34) | HTTTDP1LMNAALDH1A1KDM4E | |
| SCHEMBL29128177 | 0.77 | ALDH1A1 (0.30) | ALDH1A1KDM4EGAARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |