Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128185 | 0.87 | ALDH1A1 (0.39) | APPLMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL29128173 | 0.81 | HTT (0.40) | LMNAHTTKMT2AALDH1A1TDP1 | |
| SCHEMBL29128368 | 0.79 | ALDH1A1 (0.49) | LMNAHTTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29128376 | 0.79 | KMT2A (0.31) | LMNAHTTKMT2AALDH1A1 | |
| SCHEMBL29128402 | 0.78 | RAB9A (0.34) | LMNAHTTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29128420 | 0.76 | MEN1 (0.40) | HTTKMT2ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL29128384 | 0.74 | HTR1B (0.36) | LMNAKMT2ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL29128367 | 0.73 | KDM4E (0.44) | LMNAKMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL29128179 | 0.73 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1POLBTDP1MAPT | |
| SCHEMBL30799894 | 0.71 | RAB9A (0.46) | LMNAHTTKMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |