Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.42 |
| ▸ | RAB9A | P51151 | 10/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128208 | 0.84 | NPC1 (0.40) | NPC1RAB9APOLBKDM4EL3MBTL1 | |
| SCHEMBL29128485 | 0.84 | NPC1 (0.55) | NPC1RAB9APOLBL3MBTL1KMT2A | |
| SCHEMBL29128233 | 0.81 | MAOB (0.43) | NPC1RAB9APOLBKDM4EL3MBTL1 | |
| SCHEMBL29128481 | 0.77 | DAO (0.45) | NPC1RAB9APOLBL3MBTL1KMT2A | |
| SCHEMBL21321381 | 0.75 | POLB (0.36) | POLBL3MBTL1 | |
| SCHEMBL29128191 | 0.74 | FAAH (0.30) | — | |
| SCHEMBL29181366 | 0.70 | PPARA (0.53) | PPARAMAOAMAOB | |
| SCHEMBL29128389 | 0.69 | NISCH (0.45) | NPC1RAB9AL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL29128411 | 0.68 | NPC1 (0.52) | NPC1RAB9APOLBL3MBTL1KMT2A | |
| SCHEMBL30799977 | 0.68 | DAO (0.50) | MAOAACHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |