SCHEMBL29128481

SCHEMBL29128481

O=c1[nH]cc(COc2ccccc2)o1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 3/20 0.45
RAB9A P51151 5/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
NPC1 O15118 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
MAOB P27338 2/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B3 P37058 1/20 0.38
MAPT P10636 1/20 0.38
ALDH1A1 P00352 2/20 0.38
POLB P06746 1/20 0.38
NSD2 O96028 1/20 0.38
ABL1 P00519 1/20 0.38
PPARG P37231 1/20 0.38
RIN1 Q13671 1/20 0.38
NCOR2 Q9Y618 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30799853 0.87 KDM4E (0.42) DAOSMN1; SMN2L3MBTL1ALDH1A1NSD2
SCHEMBL29128353 0.87 KDM4E (0.42) DAOSMN1; SMN2L3MBTL1ALDH1A1NSD2
SCHEMBL29128233 0.83 MAOB (0.43) RAB9ASMN1; SMN2NPC1L3MBTL1TDP1
SCHEMBL29128295 0.82 DAO (0.50) DAOMAOBMAOA
SCHEMBL30799977 0.82 DAO (0.50) DAOMAOBMAOA
SCHEMBL29128485 0.81 NPC1 (0.55) RAB9ASMN1; SMN2NPC1L3MBTL1TDP1
SCHEMBL29128414 0.79 SMN1; SMN2 (0.44) DAORAB9ASMN1; SMN2NPC1L3MBTL1
SCHEMBL29128213 0.79 MAOB (0.48) SMN1; SMN2NPC1L3MBTL1MAOBMEN1
SCHEMBL29128235 0.78 PKM (0.43) RAB9ASMN1; SMN2NPC1L3MBTL1TDP1
SCHEMBL29128368 0.77 ALDH1A1 (0.49) RAB9ASMN1; SMN2NPC1L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117263862-A Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof 吉首大学 2023-12-22 CN disclosed