Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128485 | 0.84 | NPC1 (0.55) | KMT2ANPC1RAB9APOLBALDH1A1 | |
| SCHEMBL29128481 | 0.83 | DAO (0.45) | MAOBMAOAKMT2ANPC1RAB9A | |
| SCHEMBL29128458 | 0.81 | NPC1 (0.42) | MAOBMAOAKMT2ANPC1RAB9A | |
| SCHEMBL29128232 | 0.79 | L3MBTL1 (0.45) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL29128446 | 0.78 | SMN1; SMN2 (0.39) | KMT2ANPC1RAB9AMEN1GAA | |
| SCHEMBL29128235 | 0.75 | PKM (0.43) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL29125722 | 0.73 | ALDH1A1 (0.52) | MAOBMAOAKMT2ANPC1RAB9A | |
| SCHEMBL29128295 | 0.73 | DAO (0.50) | MAOBMAOAACHE | |
| SCHEMBL30799977 | 0.73 | DAO (0.50) | MAOBMAOAACHE | |
| SCHEMBL30799853 | 0.72 | KDM4E (0.42) | KDM4EALDH1A1L3MBTL1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |