Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SOD1 | P00441 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128201 | 0.82 | RXRA (0.41) | RXRARXRBRAB9ANPC1KDM4E | |
| SCHEMBL29128292 | 0.80 | APP (0.41) | RXRARXRBRAB9ANPC1MAOB | |
| SCHEMBL29128393 | 0.79 | DAO (0.50) | RAB9ASOD1DAOL3MBTL1 | |
| SCHEMBL30799891 | 0.76 | RAB9A (0.42) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL29128272 | 0.76 | RAB9A (0.42) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL29128524 | 0.75 | GLRA1 (0.35) | DAOL3MBTL1KMT2A | |
| SCHEMBL29125818 | 0.73 | TSHR (0.45) | RXRARXRBRAB9ANPC1KDM4E | |
| SCHEMBL29128254 | 0.73 | MAOB (0.39) | NPC1MAOBMAOAACHESOD1 | |
| SCHEMBL30799967 | 0.73 | MAOB (0.39) | NPC1MAOBMAOAACHESOD1 | |
| SCHEMBL30800076 | 0.72 | KDM4C (0.47) | RXRARXRBRAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |