Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125892 | 0.85 | SMN1; SMN2 (0.44) | RXRARXRBLMNAHTTSMN1; SMN2 | |
| SCHEMBL15652091 | 0.83 | MAOB (0.43) | TSHRSMN1; SMN2RAB9AMAOBMAOA | |
| SCHEMBL29125705 | 0.83 | SMN1; SMN2 (0.50) | TSHRHTTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29125853 | 0.80 | DAO (0.45) | RAB9ANPC1MAOBMAOA | |
| SCHEMBL29125822 | 0.79 | RAB9A (0.54) | TSHRSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL20782346 | 0.74 | RXRA (0.42) | RXRARXRBLMNAHTTSMN1; SMN2 | |
| SCHEMBL29128526 | 0.73 | RXRA (0.44) | RXRARXRBLMNAHTTSMN1; SMN2 | |
| SCHEMBL30788473 | 0.70 | SOD1 (0.56) | TSHRLMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL29125895 | 0.70 | SOD1 (0.56) | TSHRLMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL12279053 | 0.69 | RXRA (0.72) | RXRARXRBRAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |