Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128510 | 0.81 | HTT (0.40) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL29128580 | 0.79 | ALDH1A1 (0.46) | KDM4EALDH1A1LMNATDP1RAB9A | |
| SCHEMBL29128467 | 0.78 | ADRA1D (0.34) | KDM4EALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL29128566 | 0.75 | SMN1; SMN2 (0.40) | KDM4EALDH1A1LMNATDP1MEN1 | |
| SCHEMBL29125675 | 0.74 | ALDH1A1 (0.76) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL29128339 | 0.73 | USP2 (0.32) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL29128178 | 0.72 | KDM4E (0.37) | KDM4EALDH1A1LMNARAB9AMAPT | |
| SCHEMBL29128476 | 0.72 | DPYD (0.33) | KDM4EALDH1A1TDP1MAPT | |
| SCHEMBL29128313 | 0.72 | CYP1A2 (0.32) | KDM4EALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL29128504 | 0.71 | SLC6A4 (0.36) | ALDH1A1LMNATDP1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |