Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | DPYD | Q12882 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128326 | 0.84 | ALDH1A1 (0.37) | KDM4EMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29128476 | 0.81 | DPYD (0.33) | KDM4EMAPTALDH1A1HTTDPYD | |
| SCHEMBL29128313 | 0.81 | CYP1A2 (0.32) | KDM4EMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30800062 | 0.81 | CYP1A2 (0.32) | KDM4EMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29128527 | 0.80 | HCAR2 (0.36) | KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL29128546 | 0.80 | KCNA3 (0.41) | KDM4EMAPTSMN1; SMN2ALDH1A1GPR84 | |
| SCHEMBL29128461 | 0.79 | LTA4H (0.46) | KDM4EMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29128397 | 0.77 | DAO (0.44) | KDM4EALDH1A1MEN1KMT2ADPYD | |
| SCHEMBL29128419 | 0.77 | SMN1; SMN2 (0.40) | KDM4EMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30799972 | 0.77 | DAO (0.44) | KDM4EALDH1A1MEN1KMT2ADPYD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |