Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9442684 | 0.85 | L3MBTL1 (0.58) | L3MBTL1MBTD1HRH3KCNH2HRH1 | |
| SCHEMBL28993859 | 0.83 | L3MBTL1 (0.59) | L3MBTL1MBTD1HRH3HRH1ALDH1A1 | |
| SCHEMBL2490457 | 0.82 | L3MBTL1 (0.58) | L3MBTL1MBTD1HRH3KCNH2HRH1 | |
| SCHEMBL4456128 | 0.81 | HRH3 (0.63) | HRH3KCNH2HRH1POLBMAPT | |
| SCHEMBL4700360 | 0.81 | L3MBTL1 (0.57) | L3MBTL1MBTD1HRH3KCNH2HRH1 | |
| Hydrochloric Acid SCHEMBL9449150 | 0.81 | L3MBTL1 (0.57) | L3MBTL1MBTD1HRH3KCNH2HRH1 | |
| SCHEMBL4700355 | 0.80 | L3MBTL1 (0.56) | L3MBTL1MBTD1HRH3HRH1ALDH1A1 | |
| SCHEMBL11471530 | 0.78 | MBTD1 (0.51) | L3MBTL1MBTD1HRH3HRH1ALDH1A1 | |
| SCHEMBL29300214 | 0.77 | HRH3 (0.53) | L3MBTL1MBTD1HRH3KCNH2HRH1 | |
| SCHEMBL9162804 | 0.77 | L3MBTL1 (0.56) | L3MBTL1MBTD1HRH3KCNH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117050003-A | Preparation method of 1- (3-methoxypropyl) -4-piperidinamine | 山东新时代药业有限公司 | 2023-11-14 | — | — | CN | disclosed |