Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2908407 | 0.91 | GSK3B (0.34) | GSK3AGSK3BMAPTKAT2BNPSR1 | |
| SCHEMBL2911941 | 0.90 | HDAC1 (0.34) | GSK3AGSK3BMAPTKAT2BKMT2A | |
| SCHEMBL2912527 | 0.90 | GSK3B (0.36) | GSK3AGSK3BKAT2BKMT2A | |
| SCHEMBL2907410 | 0.88 | GSK3B (0.34) | GSK3AGSK3BMAPTKAT2BMEN1 | |
| SCHEMBL2907498 | 0.87 | RAB9A (0.38) | GSK3AGSK3BMAPTRAB9AMEN1 | |
| SCHEMBL2904881 | 0.87 | RAB9A (0.39) | GSK3AGSK3BMAPTRAB9AMEN1 | |
| SCHEMBL2904688 | 0.86 | GSK3B (0.34) | GSK3AGSK3BKAT2B | |
| SCHEMBL2910651 | 0.86 | MAPT (0.36) | MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2912544 | 0.86 | CYP19A1 (0.37) | GSK3AGSK3BMAPTMEN1KMT2A | |
| SCHEMBL13455481 | 0.85 | GSK3B (0.37) | GSK3AGSK3BKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537099-B1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2010-08-11 | — | — | EP | disclosed |