Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907512 | 0.88 | GSK3A (0.32) | CDK1GSK3AGSK3B | |
| SCHEMBL2908407 | 0.87 | GSK3B (0.34) | CDK1GSK3AGSK3BNPSR1MAPT | |
| SCHEMBL2907498 | 0.87 | RAB9A (0.38) | GSK3AGSK3BKDM4EMAPTALDH1A1 | |
| SCHEMBL2912527 | 0.86 | GSK3B (0.36) | CDK1GSK3AGSK3BKMT2A | |
| SCHEMBL2904881 | 0.86 | RAB9A (0.39) | GSK3AGSK3BKDM4EMAPTALDH1A1 | |
| SCHEMBL2912926 | 0.86 | BDKRB1 (0.34) | GSK3AGSK3BNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL2910394 | 0.85 | KDM4E (0.39) | GSK3BKDM4EAHRMAPTALDH1A1 | |
| SCHEMBL2911856 | 0.84 | GSK3B (0.52) | CYP19A1CDK1GSK3AGSK3BQPCT | |
| SCHEMBL2913211 | 0.83 | POLB (0.46) | GSK3AGSK3BKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2903975 | 0.83 | POLB (0.39) | GSK3AGSK3BKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537099-B1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2010-08-11 | — | — | EP | disclosed |