Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17815796 | 0.81 | PRMT1 (0.53) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6214605 | 0.79 | MEN1 (0.53) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL12138409 | 0.79 | ALDH1A1 (0.44) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28476642 | 0.78 | BCL6 (0.41) | MAPTALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL16174808 | 0.77 | MAPT (0.51) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2708359 | 0.75 | ALDH1A1 (0.38) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7946537 | 0.75 | MEN1 (0.36) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7885090 | 0.75 | LMNA (0.41) | MAPTALDH1A1SMN1; SMN2LMNACA1 | |
| SCHEMBL10814713 | 0.75 | ALDH1A1 (0.54) | MAPTALDH1A1SMN1; SMN2IDO1LMNA | |
| SCHEMBL18803141 | 0.75 | ALDH1A1 (0.36) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247383-A | Pharmaceutical compounds, salts thereof, formulations thereof, and methods of making and using the same | 基因技术公司 | 2023-12-19 | — | — | CN | claimed |
| CN-117247383-A | Pharmaceutical compounds, salts thereof, formulations thereof, and methods of making and using the same | 基因技术公司 | 2023-12-19 | — | — | CN | disclosed |