SCHEMBL29129593

SCHEMBL29129593

C=CC(=O)NOCc1ccc(C#N)c(C(F)(F)F)c1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
RXRG P48443 1/20 0.47
AR P10275 10/20 0.46
S1PR1 P21453 2/20 0.40
TAS2R14 Q9NYV8 1/20 0.39
MAPK3 P27361 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL900308 0.81 RXRA (0.50) RXRARXRBRXRGARTAS2R14
SCHEMBL28084056 0.75 RXRA (0.63) RXRARXRBRXRGARTAS2R14
SCHEMBL21924973 0.75 TGM2 (0.54) ARTAS2R14
SCHEMBL28182410 0.72 RXRA (0.60) RXRARXRBRXRGARTAS2R14
SCHEMBL16957124 0.72 AR (0.54) RXRARXRBRXRGAR
SCHEMBL28221405 0.71 RXRA (0.52) RXRARXRBRXRGAR
SCHEMBL2222581 0.71 RXRA (0.52) RXRARXRBRXRGAR
SCHEMBL12984770 0.71 RXRA (0.79) RXRARXRBRXRGARTAS2R14
SCHEMBL28084058 0.70 RXRA (0.54) RXRARXRBRXRGAR
SCHEMBL16959706 0.70 RXRA (0.50) RXRARXRBRXRGAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114350146-B High-strength bolt material and preparation method thereof 宁波群力紧固件制造有限公司 2024-03-29 CN disclosed
CN-116084167-B Electromagnetic radiation resistant protective clothing fabric and preparation method thereof 扬州锦沃科技有限公司 2023-10-27 CN disclosed
CN-116084167-A Electromagnetic radiation resistant protective clothing fabric and preparation method thereof 扬州锦沃科技有限公司 2023-05-09 CN disclosed