Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 5/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21543826 | 0.83 | KCNA3 (0.46) | KCNA3PRKCACYP1A2CYP2C19MAPT | |
| SCHEMBL21543711 | 0.81 | CYP1A2 (0.49) | KCNA3TDP1PRKCACYP1A2CYP2C19 | |
| SCHEMBL21543827 | 0.80 | CYP2A6 (0.48) | KCNA3ALOX15TDP1CYP1A2CYP2C19 | |
| SCHEMBL30930077 | 0.79 | ALOX15 (0.43) | KCNA3ALOX15TDP1NPC1POLB | |
| SCHEMBL21543800 | 0.76 | TTR (0.46) | ALOX15TDP1POLBDDB1CRBN | |
| SCHEMBL3434411 | 0.75 | CYP3A4 (0.49) | ALOX15TDP1NPC1ALDH1A1MAPT | |
| SCHEMBL23355842 | 0.74 | MAOB (0.42) | ALOX15TDP1POLBALDH1A1MAPT | |
| SCHEMBL5837067 | 0.73 | PIM1 (0.40) | KCNA3ALOX15TDP1NPC1POLB | |
| SCHEMBL8948094 | 0.73 | TDP1 (0.48) | ALOX15TDP1NPC1POLBTYMS | |
| SCHEMBL261809 | 0.73 | TDP1 (0.48) | ALOX15TDP1NPC1POLBTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069698-A | Double-functional molecule targeting SHP2 degradation and preparation and application thereof | 苏州大学 | 2023-11-17 | — | — | CN | disclosed |