Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12526972 | 0.83 | ABL1 (0.58) | ABL1SLC6A3SLC6A4MAPTKDM4E | |
| SCHEMBL28794509 | 0.81 | AKR1C4 (0.55) | MAPTCA1CA2KDM4EGAA | |
| SCHEMBL29129851 | 0.81 | ALDH1A1 (0.43) | LMNAMAPTKDM4EPOLBGAA | |
| SCHEMBL24397958 | 0.80 | SCN9A (0.44) | KMT2AMAPTKDM4EGAAALDH1A1 | |
| SCHEMBL28219995 | 0.80 | KDM4E (0.59) | KMT2AMAPTHTTKDM4EATM | |
| SCHEMBL7461289 | 0.79 | ALDH1A1 (0.44) | ABL1MEN1LMNAKMT2AMAPT | |
| SCHEMBL28451506 | 0.78 | ALDH1A1 (0.48) | MEN1KMT2AHTTNPSR1KDM4E | |
| SCHEMBL29606233 | 0.78 | ALDH1A1 (0.48) | MEN1KMT2AHTTNPSR1KDM4E | |
| SCHEMBL423691 | 0.78 | AKR1C4 (0.60) | ABL1SLC6A3SLC6A4KDM4ESERPINH1 | |
| SCHEMBL14341400 | 0.78 | ABL1 (0.47) | ABL1SLC6A3SLC6A4MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285508-A | Preparation method of pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-117263908-A | Preparation of 1-pyridylpyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-22 | — | — | CN | disclosed |