Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | GLA | P06280 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | NNMT | P40261 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28794509 | 0.83 | AKR1C4 (0.55) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL29129851 | 0.83 | ALDH1A1 (0.43) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL24397958 | 0.81 | SCN9A (0.44) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL29129843 | 0.80 | ABL1 (0.49) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL24397796 | 0.79 | HPGD (0.48) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL29606233 | 0.76 | ALDH1A1 (0.48) | KDM4EALDH1A1GAAHTTKMT2A | |
| SCHEMBL24397792 | 0.76 | LMNA (0.54) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL28451506 | 0.76 | ALDH1A1 (0.48) | KDM4EALDH1A1GAAHTTKMT2A | |
| SCHEMBL24397879 | 0.75 | CRHR1 (0.49) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2090288 | 0.75 | RAPGEF4 (0.46) | ALDH1A1GAAMAPTHPGDPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069936-A | A kind of synthesis and its application of polyhalo pyrazoles formyl urea derivative | 江苏扬农化工股份有限公司 | 2018-05-25 | — | — | CN | disclosed |