Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCG | P05129 | 1/20 | 0.62 |
| ▸ | PRKCB | P05771 | 1/20 | 0.62 |
| ▸ | PRKCA | P17252 | 1/20 | 0.62 |
| ▸ | PRKCH | P24723 | 1/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.62 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | MARK3 | P27448 | 1/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.45 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12175438 | 0.86 | PRKCG (0.64) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL29317023 | 0.86 | PRKCG (0.62) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL25337226 | 0.85 | PRKCG (0.51) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL18918059 | 0.85 | PRKCG (0.49) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL12326970 | 0.84 | PRKCG (0.48) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL27175695 | 0.84 | PRKCG (0.60) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL29130013 | 0.82 | PRKCG (0.60) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL30958439 | 0.81 | PRKCG (0.57) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL31134659 | 0.81 | PRKCG (0.49) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL30958467 | 0.81 | PRKCG (0.56) | PRKCGPRKCBPRKCAPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239794-A1 | PKC-Theta Modulators | EXSCIENTIA AI LIMITED (GB) | 2024-07-18 | — | — | US | disclosed |
| CN-117295738-A | PKC-theta modulators | 爱智药人工智能有限公司 | 2023-12-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239794-A1 | PKC-Theta Modulators | PRKCQ, PRKCH, PRKCZ | PRKCG 7/4885PRKCB 6/4885PRKCA 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.