SCHEMBL30958467

SCHEMBL30958467

COC(=O)Cc1cn(C2CCN(C(=O)OC(C)(C)C)CC2)c2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCG P05129 1/20 0.56
PRKCB P05771 1/20 0.56
PRKCA P17252 1/20 0.56
PRKCH P24723 1/20 0.56
PRKCE Q02156 1/20 0.56
PRKCD Q05655 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.50
CHRM2 P08172 1/20 0.46
CHRM4 P08173 1/20 0.46
CHRM1 P11229 1/20 0.46
CHRM3 P20309 1/20 0.46
KDM4E B2RXH2 2/20 0.46
PKM P14618 1/20 0.45
GPR119 Q8TDV5 3/20 0.44
STS P08842 1/20 0.43
OPRM1 P35372 1/20 0.42
OPRL1 P41146 1/20 0.42
ALDH1A1 P00352 1/20 0.42
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL840578 0.86 MAPK8 (0.48) PRKCGPRKCBPRKCAPRKCHPRKCE
SCHEMBL24117804 0.84 OPRL1 (0.49) KDM4EOPRM1OPRL1ALDH1A1PTGDR2
Hydrochloric Acid SCHEMBL30958427 0.81 HTR6 (0.47) PRKCGPRKCBPRKCAPRKCHPRKCE
SCHEMBL12175438 0.81 PRKCG (0.64) PRKCGPRKCBPRKCAPRKCHPRKCE
SCHEMBL29130004 0.81 PRKCG (0.62) PRKCGPRKCBPRKCAPRKCHPRKCE
SCHEMBL29317023 0.81 PRKCG (0.62) PRKCGPRKCBPRKCAPRKCHPRKCE
SCHEMBL30958419 0.80 PTGDR2 (0.44) OPRM1OPRL1ALDH1A1PTGDR2
SCHEMBL30958439 0.80 PRKCG (0.57) PRKCGPRKCBPRKCAPRKCHPRKCE
SCHEMBL17102879 0.80 L3MBTL1 (0.56) L3MBTL1CHRM2CHRM4CHRM1CHRM3
SCHEMBL27175695 0.79 PRKCG (0.60) PRKCGPRKCBPRKCAPRKCHPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4654966-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF OBESITY AND DISEASES ASSOCIATED WITH FAT CELL ENLARGEMENT MELLICELL, INC. (US) 2025-12-03 EP disclosed
WO-2024159211-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF OBESITY AND DISEASES ASSOCIATED WITH FAT CELL ENLARGEMENT MELLICELL, INC. (US) 2024-08-02 WO disclosed