Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5018970 | 0.83 | L3MBTL1 (0.43) | KDM4AL3MBTL1GRM2CACNA1HCACNA1B | |
| SCHEMBL21593060 | 0.82 | KDM4A (0.44) | KDM4AL3MBTL1GRM2CACNA1HCACNA1B | |
| SCHEMBL23418026 | 0.81 | GRM2 (0.44) | KDM4AL3MBTL1GRM2CACNA1HCACNA1B | |
| SCHEMBL18854481 | 0.81 | EPAS1 (0.43) | KDM4AL3MBTL1GRM2CACNA1HCACNA1B | |
| SCHEMBL615759 | 0.80 | KDM4A (0.42) | KDM4AL3MBTL1GRM2CACNA1HCACNA1B | |
| SCHEMBL13055397 | 0.80 | KDM4A (0.51) | KDM4AL3MBTL1CACNA1HCACNA1BCACNA1C | |
| SCHEMBL31431349 | 0.80 | GRM2 (0.41) | KDM4AL3MBTL1GRM2CACNA1HCACNA1B | |
| SCHEMBL12791343 | 0.79 | GRM2 (0.46) | KDM4AL3MBTL1GRM2CACNA1HCACNA1B | |
| SCHEMBL18578805 | 0.79 | GRM2 (0.43) | KDM4AL3MBTL1GRM2CACNA1HCACNA1B | |
| SCHEMBL21089614 | 0.78 | GLS (0.42) | KDM4AL3MBTL1GRM2CACNA1HCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295736-A | Benzo [ C ] [2,6] naphthyridine derivatives, compositions thereof and therapeutic uses thereof | 剑桥实业有限公司 | 2023-12-26 | — | — | CN | disclosed |