Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.30 |
| ▸ | GABRD | O14764 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.30 |
| ▸ | GABRE | P78334 | 2/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.30 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.30 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.30 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL866008 | 0.92 | GABRP (0.34) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Propylene Glycol SCHEMBL28102165 | 0.80 | TDP1 (0.56) | TDP1OR51E2 | |
| Propylene Glycol SCHEMBL58534 | 0.80 | TDP1 (0.56) | TDP1OR51E2 | |
| Propylene Glycol SCHEMBL28261417 | 0.80 | TDP1 (0.56) | TDP1OR51E2 | |
| SCHEMBL15920358 | 0.80 | — | — | |
| SCHEMBL3913590 | 0.80 | — | — | |
| SCHEMBL28708 | 0.80 | — | — | |
| 1,3-Butanediol SCHEMBL4324460 | 0.79 | ALDH1A1 (0.35) | TDP1THRBGABRPGABRDGABRA1 | |
| Propylene Glycol SCHEMBL29254418 | 0.79 | TDP1 (0.48) | TDP1OR51E2 | |
| Acetic Acid SCHEMBL1468433 | 0.78 | FFAR3 (0.37) | TDP1OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964697-A | Composition, cured product containing magnetic particles, magnetic particle-introduced substrate, and electronic material | 富士胶片株式会社 | 2023-10-27 | — | — | CN | disclosed |