Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14947259 | 0.84 | LMNA (0.53) | TSHRCA2CA12CA14CA7 | |
| SCHEMBL14947261 | 0.84 | LMNA (0.53) | TSHRCA2CA12CA14CA7 | |
| SCHEMBL15187313 | 0.82 | GPR84 (0.50) | TSHRCA2CA1CA12CA14 | |
| SCHEMBL28292624 | 0.82 | TSHR (0.48) | TSHRCA2CA1CA12CA14 | |
| SCHEMBL15187333 | 0.82 | GPR84 (0.50) | TSHRCA2CA1CA12CA14 | |
| SCHEMBL21694681 | 0.82 | KMT2A (0.49) | TSHRCA2CA1POLBCYP3A4 | |
| SCHEMBL17526790 | 0.80 | TSHR (0.46) | TSHRCA2CA1CA12CA14 | |
| SCHEMBL27833079 | 0.80 | CA2 (0.61) | TSHRCA2CA1CA12CA14 | |
| SCHEMBL17526664 | 0.80 | TSHR (0.46) | TSHRCA2CA1CA12CA14 | |
| SCHEMBL28795333 | 0.80 | TSHR (0.46) | TSHRCA2CA1CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304048-A | Cationic lipid | 武田药品工业株式会社 | 2023-12-29 | — | — | CN | disclosed |
| CN-112533893-B | Cationic lipid | 武田药品工业株式会社 | 2023-12-22 | — | — | CN | disclosed |