Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.39 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.39 |
| ▸ | RPS17 | P08708 | 1/20 | 0.39 |
| ▸ | RPSA | P08865 | 1/20 | 0.39 |
| ▸ | RPS2 | P15880 | 1/20 | 0.39 |
| ▸ | RPL35A | P18077 | 1/20 | 0.39 |
| ▸ | RPL7 | P18124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL29130244 | 0.95 | ASAH2 (0.49) | ASAH2MAPTALDH1A1KDM4ENPC1 | |
| Tetrabuthylammonium SCHEMBL29130247 | 0.82 | HTT (0.38) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT | |
| Tetrabuthylammonium SCHEMBL29130255 | 0.80 | HSD17B10 (0.44) | ALDH1A1CA1CA2 | |
| SCHEMBL298339 | 0.78 | ALDH1A1 (0.59) | MAPTALDH1A1KDM4ENPC1CA12 | |
| SCHEMBL3917351 | 0.78 | ALDH1A1 (0.59) | MAPTALDH1A1KDM4ENPC1CA12 | |
| SCHEMBL1317230 | 0.78 | ALDH1A1 (0.59) | MAPTALDH1A1KDM4ENPC1CA12 | |
| Tetrabuthylammonium SCHEMBL28251083 | 0.77 | ALDH1A1 (0.54) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| Tetrabuthylammonium SCHEMBL16968724 | 0.75 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6157121 | 0.74 | ALDH1A1 (0.60) | MAPTALDH1A1KDM4ENPC1MEN1 | |
| Tetrabuthylammonium SCHEMBL8417072 | 0.74 | PKM (0.50) | ASAH2MAPTALDH1A1KDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164505-A | Method for synthesizing organic sulfate by dialkyl sulfate or pyrosulfate | 湖南大学 | 2023-12-05 | — | — | CN | disclosed |