Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 4/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL29130259 | 0.93 | HSD17B10 (0.45) | HSD17B10MMP13MMP9MMP1ADAM17 | |
| Tetrabuthylammonium SCHEMBL29130247 | 0.83 | HTT (0.38) | MMP2FAAHALDH1A1 | |
| Tetrabuthylammonium SCHEMBL29130239 | 0.80 | ASAH2 (0.49) | ALDH1A1CA1CA2 | |
| Sulfuric Acid SCHEMBL22498737 | 0.76 | CA1 (0.51) | MMP13MMP9MMP1MMP2ALDH1A1 | |
| Tetrabuthylammonium SCHEMBL29130244 | 0.75 | ASAH2 (0.49) | ALDH1A1CA1CA2 | |
| Acetic Acid SCHEMBL28696150 | 0.74 | MMP9 (0.43) | HSD17B10MMP13MMP9MMP1ADAM17 | |
| Tetrabuthylammonium SCHEMBL337205 | 0.74 | FAAH (0.40) | FAAHALDH1A1CA1CA2 | |
| Tetrabuthylammonium SCHEMBL827109 | 0.74 | FAAH (0.40) | FAAHALDH1A1CA1CA2 | |
| Tetrabuthylammonium SCHEMBL29130277 | 0.74 | KDM4E (0.42) | ALDH1A1CA1CA2 | |
| SCHEMBL343939 | 0.73 | CA1 (0.55) | ALDH1A1CA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164505-A | Method for synthesizing organic sulfate by dialkyl sulfate or pyrosulfate | 湖南大学 | 2023-12-05 | — | — | CN | disclosed |