Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | CXCR4 | P61073 | 12/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | CCR2 | P41597 | 1/20 | 0.59 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001038 | 0.84 | USP2 (0.71) | SIGMAR1CXCR4HRH3MEN1CHRM2 | |
| SCHEMBL1259387 | 0.82 | CXCR4 (0.81) | SIGMAR1CXCR4HRH3MEN1CHRM2 | |
| Hydrochloric Acid SCHEMBL5573232 | 0.82 | CXCR4 (0.78) | SIGMAR1CXCR4HRH3MEN1CHRM2 | |
| SCHEMBL16307722 | 0.82 | SIGMAR1 (0.59) | SIGMAR1CXCR4HRH3MEN1CHRM2 | |
| SCHEMBL13995933 | 0.82 | USP2 (0.69) | SIGMAR1CXCR4HRH3MEN1CHRM2 | |
| Hydrochloric Acid SCHEMBL19457676 | 0.82 | USP2 (0.69) | SIGMAR1CXCR4HRH3MEN1CHRM2 | |
| Hydrochloric Acid SCHEMBL28656101 | 0.81 | CXCR4 (0.60) | SIGMAR1CXCR4HRH3MEN1CHRM2 | |
| Bromide SCHEMBL1257550 | 0.81 | CXCR4 (0.78) | SIGMAR1CXCR4HRH3MEN1CHRM2 | |
| SCHEMBL2324448 | 0.80 | SIGMAR1 (0.57) | SIGMAR1CXCR4HRH3MEN1CHRM2 | |
| SCHEMBL1978437 | 0.79 | LMNA (0.61) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954525-B | Prodrugs of fused bicyclic C5aR antagonists | 凯莫森特里克斯股份有限公司 | 2023-12-26 | — | — | CN | disclosed |