Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38659199 | 0.86 | CHRM3 (0.60) | SIGMAR1CHRM3CXCR4FAAH | |
| SCHEMBL639856 | 0.86 | CHRM3 (0.60) | SIGMAR1CHRM3CXCR4FAAH | |
| SCHEMBL21961925 | 0.81 | SIGMAR1 (0.71) | SIGMAR1CXCR4HRH3MEN1CHRM2 | |
| SCHEMBL1259602 | 0.81 | SIGMAR1 (0.71) | SIGMAR1CXCR4HRH3MEN1CHRM2 | |
| SCHEMBL6409204 | 0.81 | NCF1 (0.60) | CXCR4HRH3MEN1KMT2A | |
| SCHEMBL3839191 | 0.81 | HRH3 (0.60) | SIGMAR1HRH3FAAH | |
| SCHEMBL29130396 | 0.80 | SIGMAR1 (0.59) | SIGMAR1CXCR4HRH3MEN1CHRM2 | |
| Bromide SCHEMBL1259195 | 0.80 | SIGMAR1 (0.69) | SIGMAR1CXCR4HRH3MEN1CHRM2 | |
| Hydrochloric Acid SCHEMBL7426481 | 0.80 | CXCR4 (0.60) | SIGMAR1CHRM3CXCR4HRH3MEN1 | |
| SCHEMBL6858101 | 0.76 | SIGMAR1 (0.62) | SIGMAR1CHRM3CXCR4HRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |