Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10013759 | 0.83 | MAOB (0.60) | BCHEPOLBALDH1A1MAOBNPC1 | |
| SCHEMBL27445939 | 0.81 | CYP3A4 (0.45) | BCHEALDH1A1KMT2AMEN1ACHE | |
| SCHEMBL6242893 | 0.81 | LMNA (0.49) | BCHEALDH1A1KMT2AGAAMAPT | |
| SCHEMBL27766267 | 0.79 | KMT2A (0.50) | BCHEALDH1A1NPC1KMT2ARAB9A | |
| SCHEMBL29228866 | 0.78 | ACHE (0.49) | BCHEMAOBMAOAACHEFAAH | |
| SCHEMBL27410608 | 0.78 | ACHE (0.44) | BCHEMAOBKMT2AMEN1ACHE | |
| SCHEMBL8519068 | 0.78 | BCHE (0.59) | BCHEPOLBALDH1A1MAOBNPC1 | |
| SCHEMBL1035304 | 0.75 | POLB (0.52) | POLBALDH1A1MAOBNPC1KMT2A | |
| SCHEMBL1244858 | 0.75 | ACHE (0.58) | POLBALDH1A1MAOBNPC1KMT2A | |
| SCHEMBL2635319 | 0.74 | BCHE (0.39) | BCHEPOLBNPC1RAB9AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111491939-B | Immunoproteasome inhibitors | 普林斯匹亚生物制药公司 | 2023-12-26 | — | — | CN | disclosed |