SCHEMBL29130636

SCHEMBL29130636

Cc1cc(C)c(C(=O)C(O)c2ccccc2)c(C)c1.O=P

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.52
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
MAPK1 P28482 1/20 0.47
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 1/20 0.45
HPGD P15428 2/20 0.43
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NPSR1 Q6W5P4 2/20 0.39
GAA P10253 1/20 0.38
HTT P42858 1/20 0.38
MCOLN3 Q8TDD5 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
BRD4 O60885 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5999762 0.98 LMNA (0.53) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL4067604 0.89 LMNA (0.45) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL954446 0.88 LMNA (0.44) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL2035885 0.88 LMNA (0.44) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL2035884 0.88 LMNA (0.44) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL1150849 0.88 LMNA (0.44) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL14659767 0.88 LMNA (0.44) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL28390323 0.82 LMNA (0.45) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL18823101 0.82 L3MBTL1 (0.52) LMNAALDH1A1HPGDSLC6A2SLC6A4
SCHEMBL14781389 0.82 SRC (0.47) LMNAALDH1A1HPGDSLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111634033-B Method for producing hard-coated resin body 尼德克株式会社 2023-12-29 CN disclosed