SCHEMBL29130992

SCHEMBL29130992

CCc1nc(S(=O)(=O)CC)ccc1Br

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 1/20 0.32
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
CCR4 P51679 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30602421 1.00 PSIP1 (0.32) PSIP1MEN1NPC1RAB9AKMT2A
SCHEMBL21916273 0.78 KDM4E (0.40) PSIP1MEN1NPC1RAB9AKMT2A
SCHEMBL29131020 0.78 ESR1 (0.33) PSIP1
SCHEMBL29131002 0.78 PSIP1 (0.32) PSIP1
SCHEMBL15691380 0.78 PSIP1 (0.32) PSIP1MEN1NPC1RAB9AKMT2A
SCHEMBL30602438 0.78 PSIP1 (0.32) PSIP1
SCHEMBL30602459 0.78 ESR1 (0.33) PSIP1
SCHEMBL29130926 0.75 ALDH1A1 (0.36) PSIP1NPC1RAB9ACCR4
SCHEMBL30602409 0.75 ALDH1A1 (0.36) PSIP1NPC1RAB9ACCR4
SCHEMBL29131009 0.74 CDK1 (0.41) MEN1KMT2ACCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069724-A Fused ring compounds, pharmaceutical compositions and uses 上海赛默罗德生物科技有限公司 2023-11-17 CN disclosed