SCHEMBL29131002

SCHEMBL29131002

CCS(=O)(=O)c1ccc(Br)c(Cl)n1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 1/20 0.32
MBOAT4 Q96T53 1/20 0.31
TSHR P16473 2/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30602438 1.00 PSIP1 (0.32) PSIP1MBOAT4TSHRALDH1A1
SCHEMBL517159 0.79 ALDH1A1 (0.38) ALDH1A1
SCHEMBL30602421 0.78 PSIP1 (0.32) PSIP1
SCHEMBL29131020 0.78 ESR1 (0.33) PSIP1
SCHEMBL30602459 0.78 ESR1 (0.33) PSIP1
SCHEMBL29130992 0.78 PSIP1 (0.32) PSIP1
SCHEMBL4658234 0.77
SCHEMBL30602409 0.75 ALDH1A1 (0.36) PSIP1MBOAT4ALDH1A1
SCHEMBL29130926 0.75 ALDH1A1 (0.36) PSIP1MBOAT4ALDH1A1
SCHEMBL30602403 0.74 CDK1 (0.41) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069724-A Fused ring compounds, pharmaceutical compositions and uses 上海赛默罗德生物科技有限公司 2023-11-17 CN disclosed