Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20782379 | 0.78 | MAT2A (0.36) | BRD9BRD7MAT2AALDH1A1GAA | |
| SCHEMBL29130901 | 0.77 | LRRK2 (0.31) | MAT2AALDH1A1GAASMN1; SMN2NPC1 | |
| SCHEMBL11159798 | 0.74 | KDM4E (0.32) | ALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL16869991 | 0.72 | AURKA (0.33) | — | |
| SCHEMBL29038170 | 0.68 | HTT (0.37) | HTT | |
| SCHEMBL1357367 | 0.67 | — | — | |
| SCHEMBL15396848 | 0.66 | ALDH1A1 (0.41) | ALDH1A1GAAHPGDMAPTNPSR1 | |
| SCHEMBL17450949 | 0.65 | CA2 (0.42) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL18052191 | 0.65 | — | — | |
| SCHEMBL2515269 | 0.64 | KDM4E (0.34) | ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069724-A | Fused ring compounds, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-17 | — | — | CN | disclosed |