Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 7/20 | 0.34 |
| ▸ | USP8 | P40818 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602373 | 1.00 | TXNRD1 (0.37) | TXNRD1CCR4USP8NQO2OGA | |
| SCHEMBL29131025 | 0.85 | CCR4 (0.33) | CCR4USP8NQO2ROCK2MAPT | |
| SCHEMBL30602426 | 0.85 | CCR4 (0.33) | CCR4USP8NQO2ROCK2MAPT | |
| SCHEMBL2826186 | 0.79 | CCR4 (0.35) | CCR4NQO2ROCK2MAPTEDNRA | |
| SCHEMBL29130926 | 0.78 | ALDH1A1 (0.36) | TXNRD1CCR4NQO2ROCK2MAPT | |
| SCHEMBL30602409 | 0.78 | ALDH1A1 (0.36) | TXNRD1CCR4NQO2ROCK2MAPT | |
| SCHEMBL19951522 | 0.77 | EDNRA (0.33) | TXNRD1EDNRAKMT2A | |
| SCHEMBL29130990 | 0.74 | ALDH1A1 (0.36) | TXNRD1CCR4NQO2MAPTEDNRA | |
| SCHEMBL30602425 | 0.74 | ALDH1A1 (0.36) | TXNRD1CCR4NQO2MAPTEDNRA | |
| SCHEMBL29130928 | 0.73 | RIPK1 (0.34) | TXNRD1CCR4NQO2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069724-A | Fused ring compounds, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-17 | — | — | CN | disclosed |