SCHEMBL29131301

SCHEMBL29131301

O=C(O)C(C(=O)O)[S+]([O-])Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
ALPI P09923 1/20 0.44
PKM P14618 1/20 0.44
PTGS1 P23219 1/20 0.44
XIAP P98170 1/20 0.44
SLC7A5 Q01650 1/20 0.44
CPA3 P15088 3/20 0.43
AKR1B1 P15121 1/20 0.41
CPA1 P15085 6/20 0.41
FOLH1 Q04609 1/20 0.41
CPB1 P15086 1/20 0.41
CPB2 Q96IY4 1/20 0.41
SRR Q9GZT4 2/20 0.40
SLC1A3 P43003 1/20 0.40
SLC1A2 P43004 1/20 0.40
SLC1A1 P43005 1/20 0.40
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29131299 1.00 CYP1A2 (0.47) CYP1A2CES2CES1ALPIPKM
SCHEMBL10804715 0.82 CYP1A2 (0.45) CYP1A2CES2CES1ALPIPKM
SCHEMBL10805190 0.79 CYP1A2 (0.42) CYP1A2CES2CES1ALPIPKM
SCHEMBL29131288 0.78 MMP8 (0.48) HSD17B10
SCHEMBL29131350 0.78 MMP8 (0.48) HSD17B10
SCHEMBL10256504 0.74 CES1 (0.50) CYP1A2CES2CES1ALPIPKM
SCHEMBL11414552 0.73 CPA1 (0.44) CES2CES1ALPIPKMPTGS1
Acetone SCHEMBL26919912 0.72 CES2 (0.48) CYP1A2CES2CES1ALPIPKM
SCHEMBL14215516 0.72 APAF1 (0.40) CYP1A2CES2CES1ALPIPKM
SCHEMBL29525090 0.72 SLC7A5 (0.55) CYP1A2CES2CES1ALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117303992-A Preparation method of polyfunctional group substituted chiral sulfoxide compound 厦门大学 2023-12-29 CN disclosed