SCHEMBL29131638

SCHEMBL29131638

N[C@@H](Cc1ccccc1)C(=O)Oc1ccc(C(=O)[C@@H]2CCCN2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSC P53634 2/20 0.46
HTR2C P28335 1/20 0.44
HTR2B P41595 1/20 0.44
HDAC1 Q13547 3/20 0.40
HDAC3 O15379 2/20 0.40
HDAC2 Q92769 1/20 0.40
ALPI P09923 1/20 0.40
PKM P14618 1/20 0.40
PTGS1 P23219 1/20 0.40
XIAP P98170 1/20 0.40
SLC7A5 Q01650 1/20 0.40
DPP4 P27487 2/20 0.39
DPP8 Q6V1X1 2/20 0.39
DPP9 Q86TI2 2/20 0.39
DPP7 Q9UHL4 2/20 0.39
TYR P14679 1/20 0.39
HRH2 P25021 2/20 0.38
HRH1 P35367 2/20 0.38
FAP Q12884 1/20 0.38
ELANE P08246 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10757105 0.87 HTR2C (0.45) CTSCHTR2CHTR2BHDAC1HDAC3
SCHEMBL6284117 0.86 SLC7A5 (0.46) CTSCHTR2CHTR2BALPIPKM
SCHEMBL29131652 0.81 ELANE (0.40) HTR2CHDAC1HDAC3HDAC2DPP4
SCHEMBL498386 0.80 CTSC (0.50) CTSCHTR2CHTR2BALPIPKM
SCHEMBL3726266 0.80 CTSC (0.50) CTSCHTR2CHTR2BALPIPKM
SCHEMBL2478803 0.80 CTSC (0.50) CTSCHTR2CHTR2BALPIPKM
Phenylalanine Methyl Ester SCHEMBL29087592 0.78 CTSC (0.51) CTSCHTR2CHTR2BALPIPKM
Phenylalanine Methyl Ester SCHEMBL27741689 0.78 CTSC (0.51) CTSCHTR2CHTR2BALPIPKM
SCHEMBL5576438 0.77 SLC7A5 (0.41) CTSCHTR2CHTR2BALPIPKM
SCHEMBL4542258 0.77 PTPN1 (0.45) CTSCHTR2CHTR2BALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117269494-A A group of metabolic markers for breast cancer lung metastasis 厦门大学 2023-12-22 CN disclosed