Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Proline SCHEMBL17728310 | 0.96 | PTPN1 (0.43) | PTPN1SLC7A5ITGB3ITGA2BPTGS1 | |
| Threonine SCHEMBL17728293 | 0.89 | SLC7A5 (0.37) | PTPN1SLC7A5ITGB3ITGA2BPTGS1 | |
| Proline SCHEMBL17728296 | 0.88 | HTR2C (0.37) | PTPN1SLC7A5ITGB3ITGA2BPTGS1 | |
| SCHEMBL3100802 | 0.88 | ITGB3 (0.38) | PTPN1SLC7A5ITGB3ITGA2BPTGS1 | |
| Alanine SCHEMBL1826638 | 0.88 | SLC7A5 (0.37) | PTPN1SLC7A5ITGB3ITGA2BPTGS1 | |
| SCHEMBL17728295 | 0.88 | HTR2C (0.36) | PTPN1SLC7A5ITGB3ITGA2BPTGS1 | |
| SCHEMBL5576438 | 0.87 | SLC7A5 (0.41) | PTPN1SLC7A5ITGB3ITGA2BPTGS1 | |
| SCHEMBL1675509 | 0.86 | SLC7A5 (0.44) | PTPN1SLC7A5ITGB3ITGA2BHTR2C | |
| Tyrosine SCHEMBL4352798 | 0.84 | SLC7A5 (0.57) | PTPN1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL6284117 | 0.83 | SLC7A5 (0.46) | PTPN1SLC7A5ITGB3ITGA2BPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112813064-A | Method for creating endogenous herbicide-resistant rice with high and stable resistance | 安徽省农业科学院水稻研究所 | 2021-05-18 | — | — | CN | disclosed |
| WO-2020245748-A1 | METHODS AND SYSTEMS FOR ASSESSING A PHENOTYPE OF A BIOLOGICAL TISSUE OF A PATIENT USING RAMAN SPECTROSCOPY | POLYVALOR, LIMITED PARTNERSHIP (CA) | 2020-12-10 | — | — | WO | disclosed |
| WO-2012062906-A1 | PEPTIDES AS BIOACTIVE COMPOUNDS | INSTITUTO BIOMAR, S.A. (ES) | 2012-05-18 | — | — | WO | disclosed |
| EP-1202963-B1 | SPLA2 INHIBITORS | LILLY CO ELI (US) | 2007-01-03 | — | — | EP | disclosed |
| US-6900238-B1 | HIV protease inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-05-31 | — | — | US | disclosed |
| EP-0873519-A4 | HIV PROTEASE INHIBITORS | SCRIPPS RESEARCH INST (US) | 2005-04-27 | — | — | EP | disclosed |
| EP-0873519-A1 | HIV PROTEASE INHIBITORS | The Scripps Research Institute (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997021100-A9 | HIV PROTEASE INHIBITORS | — | 1997-10-30 | — | — | WO | disclosed |
| WO-1997021100-A1 | HIV PROTEASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-06-12 | — | — | WO | disclosed |
| US-4473646-A | SEPARATION OF ISOMERS, PURIFICATION | DEVELOPMENT FINANCE CORP. OF NEW ZEALAND (NZ) | 1984-09-25 | — | — | US | disclosed |
| US-4064235-A | INCREASING RENAL BLOOD FLOW | EISAI CO., LTD. (JA) | 1977-12-20 | — | — | US | disclosed |
| US-4064235-A | INCREASING RENAL BLOOD FLOW | EISAI CO., LTD. (JA) | 1977-12-20 | — | — | US | disclosed |