Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 6/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | KMT5B | Q4FZB7 | 1/20 | 0.32 |
| ▸ | KMT5C | Q86Y97 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31178702 | 0.75 | ALDH1A1 (0.33) | YTHDC1CYP1A2TSHRCYP2C19ALDH1A1 | |
| SCHEMBL31138557 | 0.75 | YTHDC1 (0.41) | YTHDC1CYP1A2TSHRCYP2C19ALDH1A1 | |
| SCHEMBL4752520 | 0.73 | CYP2C19 (0.40) | YTHDC1ATRCYP1A2TSHRCYP2C19 | |
| SCHEMBL31750935 | 0.73 | YTHDC1 (0.35) | YTHDC1ATRCYP1A2TSHRCYP2C19 | |
| SCHEMBL476839 | 0.72 | HPGD (0.37) | YTHDC1CYP1A2TSHRCYP2C19ALDH1A1 | |
| SCHEMBL31179407 | 0.72 | ATR (0.38) | ATRTSHRKDM4EKMT2AABL1 | |
| SCHEMBL25189871 | 0.69 | ALDH1A1 (0.38) | YTHDC1CYP1A2TSHRCYP2C19KDM4E | |
| SCHEMBL15401068 | 0.68 | YTHDC1 (0.36) | YTHDC1CYP2C19CYP4F2CYP4A11BRAF | |
| SCHEMBL28801167 | 0.68 | RET (0.35) | ATRCYP2C19CYP4F2CYP4A11MEN1 | |
| SCHEMBL3953322 | 0.68 | NOS1 (0.43) | YTHDC1ATRCYP1A2TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098763-A | TYK2 inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| EP-4274832-A1 | TYK2 INHIBITORS | Biogen MA Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022150446-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2022-07-14 | — | — | WO | disclosed |