Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10959895 | 0.80 | NPSR1 (0.50) | HTTMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL29131988 | 0.80 | HTT (0.42) | RIPK1HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7034982 | 0.77 | KMT2A (0.47) | RIPK1HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL19570751 | 0.75 | NPSR1 (0.61) | HTTMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL11882082 | 0.75 | NPSR1 (0.45) | HTTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7800481 | 0.74 | RIPK1 (0.72) | RIPK1HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL1856168 | 0.73 | HDAC8 (0.47) | RIPK1HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL3279004 | 0.72 | ALOX5 (0.60) | RIPK1HTTALOX5LMNAPTGS1 | |
| SCHEMBL6626142 | 0.71 | KMT2A (0.46) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL1436622 | 0.71 | ALOX5 (0.70) | RIPK1MEN1KMT2AALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716343-B | Novel NAMPT enzyme agonist, preparation and application thereof | 清华大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-114716343-A | Novel NAMPT enzyme agonist, preparation and application thereof | 清华大学 | 2022-07-08 | — | — | CN | disclosed |