Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132308 | 0.89 | KDM4E (0.35) | KDM4EPKMGPR119BACE1DDB1 | |
| SCHEMBL29132160 | 0.87 | EPHX2 (0.37) | GPR119DDB1CRBNNR1H2USP1 | |
| SCHEMBL29927199 | 0.86 | PDK1 (0.45) | KDM4EPKMGPR119KDM1A | |
| SCHEMBL26926046 | 0.85 | KDM4E (0.45) | KDM4EPKMGPR119BACE1NR1H2 | |
| SCHEMBL26926054 | 0.85 | KDM4E (0.45) | KDM4EPKMGPR119BACE1NR1H2 | |
| SCHEMBL26926233 | 0.85 | KDM4E (0.45) | KDM4EPKMGPR119BACE1NR1H2 | |
| SCHEMBL29132136 | 0.82 | PRKCB (0.34) | — | |
| SCHEMBL29132221 | 0.81 | EPHX2 (0.36) | GPR119DDB1CRBNNR1H2EPHX2 | |
| SCHEMBL29132076 | 0.79 | NR1H2 (0.45) | KDM4EPKMGPR119NR1H2EPHX2 | |
| SCHEMBL29132073 | 0.79 | NR1H2 (0.45) | KDM4EPKMGPR119NR1H2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321046-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-12-29 | — | — | CN | disclosed |