Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.55 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132048 | 0.96 | GPR119 (0.57) | GPR119USP30 | |
| SCHEMBL21456063 | 0.86 | GPR119 (0.53) | GPR119 | |
| SCHEMBL21405347 | 0.86 | GPR119 (0.53) | GPR119 | |
| SCHEMBL23205355 | 0.86 | GPR119 (0.53) | GPR119 | |
| SCHEMBL30179976 | 0.85 | GPR119 (0.54) | GPR119 | |
| SCHEMBL901264 | 0.85 | GPR119 (0.54) | GPR119 | |
| SCHEMBL29132200 | 0.83 | GPR119 (0.54) | GPR119USP30 | |
| SCHEMBL29132224 | 0.82 | GPR119 (0.53) | GPR119 | |
| SCHEMBL29132112 | 0.81 | GPR119 (0.48) | GPR119USP30HRH3 | |
| SCHEMBL21644754 | 0.81 | GPR119 (0.51) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308557-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-117321046-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-12-29 | — | — | CN | disclosed |
| WO-2022198112-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2022-09-22 | — | — | WO | disclosed |