SCHEMBL30179976

SCHEMBL30179976

CC(C)(C)OC(=O)N1CCN(c2cc(Br)ccn2)CC1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 8/20 0.54
CKS1B P61024 2/20 0.52
SKP1 P63208 2/20 0.52
SKP2 Q13309 2/20 0.52
LRRK2 Q5S007 1/20 0.51
MAP4K4 O95819 1/20 0.50
ACHE P22303 1/20 0.47
POLB P06746 1/20 0.47
BACE1 P56817 2/20 0.47
RET P07949 2/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
WNT3A P56704 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL901264 1.00 GPR119 (0.54) GPR119CKS1BSKP1SKP2LRRK2
SCHEMBL11963375 0.95 CKS1B (0.55) GPR119CKS1BSKP1SKP2LRRK2
SCHEMBL29132224 0.90 GPR119 (0.53) GPR119CKS1BSKP1SKP2LRRK2
SCHEMBL15228419 0.87 GPR119 (0.56) GPR119CKS1BSKP1SKP2LRRK2
SCHEMBL29132048 0.86 GPR119 (0.57) GPR119
SCHEMBL24671505 0.86 GPR119 (0.52) GPR119LRRK2
SCHEMBL29132280 0.86 GPR119 (0.52) GPR119CKS1BSKP1SKP2LRRK2
SCHEMBL30066214 0.86 GPR119 (0.52) GPR119LRRK2
SCHEMBL113805 0.86 GPR119 (0.55) GPR119CKS1BSKP1SKP2LRRK2
SCHEMBL29132285 0.85 GPR119 (0.55) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106389-A1 NMT INHIBITOR AND USE THEREOF 주식회사 이노보테라퓨틱스 2026-05-21 WO disclosed
CN-120040416-A Piperazine amide skeleton compound and application thereof 中国药科大学 2025-05-27 CN disclosed
EP-4419525-A1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER Artios Pharma Limited (GB) 2024-08-28 EP disclosed
WO-2023067353-A1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER ARTIOS PHARMA LIMITED (GB) 2023-04-27 WO disclosed
WO-2023278759-A1 MK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2023-01-05 WO disclosed