Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25204076 | 0.77 | MAPK1 (0.42) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL29132420 | 0.77 | MEN1 (0.50) | MEN1KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL156641 | 0.76 | MEN1 (0.57) | MEN1KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL17276154 | 0.69 | MEN1 (0.55) | MEN1KMT2AALDH1A1KDM4ENPSR1 | |
| SCHEMBL16505938 | 0.67 | RXRA (0.50) | MEN1KMT2AALDH1A1KDM4ENPSR1 | |
| SCHEMBL11445874 | 0.66 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL2325062 | 0.66 | OPRD1 (0.51) | MEN1KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL29271619 | 0.66 | KDM4E (0.41) | ALDH1A1L3MBTL1HPGDKDM4ENPSR1 | |
| SCHEMBL30529417 | 0.66 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4ENPSR1 | |
| SCHEMBL1529974 | 0.66 | GSK3B (0.53) | MEN1KMT2AALDH1A1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819412-B | Synthesis method and intermediate of N-heterocycle BET bromodomain inhibitor | 成都苑东生物制药股份有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-115819412-A | Synthetic method of N-heterocyclic BET bromodomain inhibitor and intermediate thereof | 成都苑东生物制药股份有限公司 | 2023-03-21 | — | — | CN | disclosed |