Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626339 | 1.00 | CYP11B1 (0.34) | CYP11B1CYP11B2NLRP3HSD17B1L3MBTL1 | |
| SCHEMBL25339114 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MAPTPTPN2 | |
| SCHEMBL29132508 | 0.80 | PTGIR (0.38) | KDM4E | |
| SCHEMBL30683967 | 0.80 | PTGIR (0.38) | KDM4E | |
| SCHEMBL7073132 | 0.71 | CYP19A1 (0.49) | HSD17B1ALDH1A1MAPTMIFTSHR | |
| SCHEMBL7077031 | 0.71 | CYP19A1 (0.49) | HSD17B1MIF | |
| SCHEMBL8328043 | 0.70 | CYP19A1 (0.50) | — | |
| SCHEMBL29113472 | 0.68 | MCHR1 (0.42) | — | |
| SCHEMBL7300384 | 0.68 | ITGB3 (0.39) | HSD17B1ALDH1A1MAPTHPGD | |
| SCHEMBL3964420 | 0.68 | HSD17B1 (0.44) | CYP11B1CYP11B2HSD17B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829555-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2023-09-29 | — | — | CN | disclosed |