Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28500315 | 0.89 | HSD11B1 (0.33) | LMNA | |
| SCHEMBL26696808 | 0.74 | ACE (0.35) | ACE | |
| SCHEMBL16032282 | 0.69 | DPP4 (0.31) | — | |
| SCHEMBL14714686 | 0.67 | HSD11B1 (0.30) | LMNA | |
| SCHEMBL26136295 | 0.66 | DPP4 (0.31) | — | |
| SCHEMBL1665466 | 0.66 | LMNA (0.31) | LMNARIPK1 | |
| SCHEMBL14637632 | 0.66 | ACE (0.31) | ACELMNACYP2C19 | |
| SCHEMBL28601614 | 0.66 | ACE (0.31) | ACE | |
| SCHEMBL28849715 | 0.65 | ALDH1A1 (0.32) | — | |
| SCHEMBL1632220 | 0.64 | FFAR3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580592-A | Compounds for targeting bruton's tyrosine kinase degradation | 渤健马萨诸塞州股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-117203202-A | Quinoxaline derivative and use thereof | 黑钻治疗公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-116867758-A | IRAK degradation agents and uses thereof | 凯麦拉医疗公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116745295-A | BRM targeting compounds and related methods of use | 普莱鲁德疗法有限公司 | 2023-09-12 | — | — | CN | disclosed |