Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127577 | 0.85 | LMNA (0.46) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL30041782 | 0.85 | LMNA (0.46) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL436238 | 0.85 | LMNA (0.46) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL29133101 | 0.84 | CTSD (0.49) | KMT2ALMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL30622195 | 0.84 | CTSD (0.49) | KMT2ALMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL31664600 | 0.83 | HSD17B10 (0.41) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL6637803 | 0.82 | GAA (0.44) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL22280616 | 0.82 | KDM4E (0.49) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL27867432 | 0.82 | LMNA (0.43) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL29133214 | 0.81 | ALDH1A1 (0.46) | KMT2ALMNAALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |