Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL27951317 | 0.83 | TRIM24 (0.47) | TRIM24TRIM33SMN1; SMN2LMNAEGFR | |
| SCHEMBL29622282 | 0.82 | — | — | |
| SCHEMBL122934 | 0.82 | — | — | |
| Formaldehyde SCHEMBL28292213 | 0.81 | SMN1; SMN2 (0.45) | TRIM24TRIM33SMN1; SMN2LMNAEGFR | |
| SCHEMBL517158 | 0.77 | LMNA (0.42) | TRIM24TRIM33SMN1; SMN2LMNAEGFR | |
| SCHEMBL29133119 | 0.75 | HTR2A (0.40) | TRIM24TRIM33ALDH1A1NFE2L2 | |
| SCHEMBL28049808 | 0.74 | CA1 (0.41) | LMNAEGFRKMT2AALDH1A1MAPT | |
| SCHEMBL27966466 | 0.73 | MEN1 (0.37) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL28275703 | 0.72 | TRIM24 (0.38) | TRIM24TRIM33SMN1; SMN2LMNARAB9A | |
| SCHEMBL29132997 | 0.71 | TRIM24 (0.33) | TRIM24TRIM33SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |