Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122934 | 0.93 | — | — | |
| SCHEMBL29622282 | 0.93 | — | — | |
| SCHEMBL517158 | 0.87 | LMNA (0.42) | SMN1; SMN2LMNATRIM24TRIM33EGFR | |
| Formic Acid SCHEMBL27951317 | 0.85 | TRIM24 (0.47) | SMN1; SMN2LMNATRIM24TRIM33EGFR | |
| SCHEMBL29132983 | 0.81 | TRIM24 (0.43) | SMN1; SMN2LMNATRIM24TRIM33EGFR | |
| Formaldehyde SCHEMBL27551738 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| Formaldehyde SCHEMBL29031592 | 0.73 | P2RX7 (0.40) | TRIM24TRIM33NPC1CDC25BAXL | |
| Formaldehyde SCHEMBL29230974 | 0.73 | NAPRT (0.45) | SMN1; SMN2LMNATRIM24TRIM33HTT | |
| Formaldehyde SCHEMBL28284792 | 0.73 | TRIM24 (0.47) | SMN1; SMN2LMNATRIM24TRIM33HTT | |
| SCHEMBL600903 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106170489-B | New Pyrazolopyrimidine derivative and its purposes as MALT1 inhibitor | 诺华股份有限公司 | 2019-05-03 | — | — | CN | disclosed |